The clinical loss of pregnancy could be caused by genetic abnormalities present in one of the parents, a uterus abnormality, use of recreational drugs during pregnancy, being overweight, excessive caffeine intake and untreated medical conditions such as thyroid disease, diabetes or thrombophilia. In over half the cases of loss of pregnancy, the exact cause remains undetermined. One loss of pregnancy does not mean the consecutive pregnancies will have problems. In fact, recurrent loss of pregnancy is quite rare and may point to a deeper genetic cause or an abnormal anatomy of the uterus that prevents attachment of the embryo to the endometrial wall.
The pregnant woman is at a risk of losing her pregnancy if she consumes drugs, alcohol or excessive caffeine. Being overweight, underweight and having thyroid disease could also put a pregnant woman at risk of miscarriage.A pregnant woman above the age of 35 has a higher risk of losing the pregnancy as well.