Overview
Primary sclerosing cholangitis is an autoimmune condition leading to inflammation and damage of the bile ducts. When the bile ducts get damaged, bile made in the liver cannot reach the small intestine to digest fats. The backed-up bile can cause inflammation and scarring in the liver. It is a chronic, progressive disease and can co-exist with certain autoimmune conditions of the intestine. It is diagnosed commonly in older children and young adults.