- The pancreas serves two main functions. The exocrine portion of the gland secrete digestive juices, while the endocrine portion secretes hormones, the most important being insulin.
- Most pancreatic malignancies are exocrine. Infiltrating ductal adenocarcinomas account for 90% of pancreatic cancers
- Pancreatic cancer is a much-feared disease due to its notoriously late presentation, early metastases and poor survival rates.
- Less than a fifth of patients present with localised, potentially curable tumours and the overall five-year survival rate remains less than 5%